Opportunity Information: Apply for HRSA 21 079
The Long-term Follow-up for Severe Combined Immunodeficiency and Other Newborn Screening Conditions grant opportunity (HRSA 21-079) is a federal funding program run by the U.S. Department of Health and Human Services through the Health Resources and Services Administration (HRSA). It is offered as a discretionary cooperative agreement, which typically means awardees do not just receive funds and operate independently; instead, they can expect active involvement and partnership from HRSA in implementing and refining the work. The program sits within the health funding area (CFDA 93.110) and is focused on improving outcomes for infants and children whose conditions are identified through state newborn screening systems.
At its core, the purpose of the opportunity is to strengthen what happens after a newborn screening result identifies a serious condition, especially severe combined immunodeficiency (SCID) and other newborn screening conditions. Newborn screening is designed to catch certain disorders early, often before symptoms appear, but identifying a condition is only the first step. This program targets the long-term follow-up (LTFU) gap by helping build and expand the capacity of state public health agencies and their partners to make sure children actually receive timely confirmatory testing, appropriate specialty care, counseling for families, and ongoing coordinated services over time. In practical terms, the program is about building a reliable system of care that follows a child beyond the initial screen, tracks outcomes, and helps ensure the screening translates into better health and survival.
A major emphasis of the NOFO is on comprehensive models of long-term follow-up that are built on real collaboration. Applicants are expected to demonstrate partnerships between clinicians (such as immunologists, geneticists, metabolic specialists, and primary care providers), public health agencies (particularly state newborn screening and child health programs), and families. The intent is to create an organized, coordinated approach that can assess needs, connect children to treatment, and manage ongoing follow-up in a way that is sustainable and measurable. This includes the idea of a system that not only refers families out but also monitors whether follow-up happened, whether treatment was started, and how the child is doing over time.
The funding details indicate a relatively competitive national program. HRSA anticipated making about six awards, with an award ceiling of $500,000 per award. The opportunity was posted on March 3, 2021, with an original application deadline of May 3, 2021. Eligibility is listed broadly as "Others," with clarification expected in the NOFO's eligibility section, but the stated goal and framing make it clear the work is designed to expand state-level public health capacity and statewide systems, often through state agencies or closely aligned entities and partnerships.
Overall, this grant opportunity is aimed at turning newborn screening results into long-term health gains by supporting end-to-end follow-up infrastructure: coordinated care pathways, counseling and services for families, collaboration across clinical and public health settings, and organized systems that can track and improve outcomes for children diagnosed through newborn screening, including high-impact conditions like SCID.Apply for HRSA 21 079
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Long-term Follow-up for Severe Combined Immunodeficiency and Other Newborn Screening Conditions" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
- This funding opportunity was created on Mar 03, 2021.
- Applicants must submit their applications by May 03, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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